If it's anything like what I had, you could just delete the Battle.net folder in AppData > Local > Blizzard Entertainment folder. Booting up SC2 will create a new one. If you have anything custom in your Cache folder inside the Battle.net folder, you'll want to back that up.
If that doesn't solve the problem, I'd do a reinstall.
If that doesn't solve the problem, I'd do a reinstall.